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Genetics news
Genetics
23andMe is potentially selling more than just genetic data. Survey info is just as much a privacy problem
As soon as the genetic testing company 23andMe filed for bankruptcy on March 23, 2025, concerns about what would happen to the personal information contained in its massive genetic and health information database were swift ...
11 hours ago
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Oncology & Cancer
Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers
In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated ...
12 hours ago
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Combination approach to advanced cancer could improve survival
An international team of researchers, including experts from the University of Adelaide, has found genomic testing and targeted therapies for patients with advanced cancer could improve survival rates by up to 40%.
16 hours ago
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Protective gene found to preserve mitochondria during kidney disease progression
Research led by Children's Hospital of Fudan University in China has found that a gene called pancreatic progenitor cell differentiation and proliferation factor (PPDPF) helps protect kidney cells by supporting enzymes involved ...
DNA mutations that contribute to spina bifida during embryogenesis open the door to potential treatments
Scientists at Rady Children's Institute for Genomic Medicine, and the Department of Neurosciences and Pediatrics at the University of California, San Diego, have made a significant breakthrough in understanding the causes ...
Apr 1, 2025
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Balance between two competing nerve proteins deters symptoms of autism in mice, study finds
In mice, autism symptoms arise when a certain pair of competing nerve proteins falls out of equilibrium, according to a study published in the open-access journal PLOS Biology by Dongdong Zhao of Wenzhou Medical University, ...
Apr 1, 2025
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Detailed atlas identifies optimal viral vectors for precise gene therapy
Gene therapy, a technique that is revolutionizing the treatment of multiple genetic conditions, including eye and muscle diseases and blood disorders, requires efficient and specific delivery of the genetic material to the ...
Apr 1, 2025
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Novel AI-based method reveals how cells respond to drug treatments
Researchers from Tel Aviv University have developed an innovative method that can help to understand better how cells behave in changing biological environments, such as those found within a cancerous tumor.
Apr 1, 2025
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How smoking and drinking alcohol causes cancer: Scientists uncover unique patterns of DNA damage
Scientists have revealed exactly how tobacco smoke damages DNA to drive the development of different types of head and neck cancer, a finding that could unlock new treatments and prevention strategies.
Mar 31, 2025
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Mouse study identifies shared genes involved in hearing and vision regeneration
The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, Ph.D., published in the Proceedings of the National Academy of ...
Mar 31, 2025
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Gene therapy reverses symptoms of rare neurological disease in animal models
A recent study led by the UAB demonstrates the potential of gene therapy to restore motor capacity in an ultra-rare disease, megalencephalic leukoencephalopathy with subcortical cysts (MLC), even when treatment begins after ...
Mar 31, 2025
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Extensive gene mapping reveals 20 variants linked to atherosclerosis risk, paving way for early detection
Swedish researchers have identified genetic variants that increase the risk of atherosclerosis. The aim is for these new findings to enable earlier detection of atherosclerosis and improved treatment of cardiovascular diseases ...
Mar 31, 2025
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Chromatin packing domains in ovarian cancer cells: A new target for therapy
Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, according to a study published in Advanced Science.
Mar 31, 2025
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New study reveals protector protein that supports hair regrowth in adults
Alopecia is an autoimmune disorder that causes non-scarring hair loss on the scalp and body that is experienced by almost 2% of the global population at some point in their lifetime.
Researchers identify mutations that can lead to resistance to some chemotherapies
Investigators at Mass General Brigham have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a pathway that harnesses reactive oxygen species (ROS) to kill cancer cells. The study ...
Mar 29, 2025
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Researchers develop new DNA test for personalized treatment of bacterial vaginosis
Roughly one out of three women ages 14-49 in the United States develop a vaginal bacterial imbalance known as bacterial vaginosis (BV) during their lifetime. BV is characterized by unpleasant odors, and potentially painful ...
Mar 29, 2025
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Genes may influence our enjoyment of music
Music is central to human emotion and culture. Does our ability to enjoy music have a biological basis? A genetic twin study, published in Nature Communications, shows that music enjoyment is partly heritable. An international ...
Mar 28, 2025
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Testing for just three genes could help prevent 75% of avoidable side effects for certain medications
A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent ...
Mar 27, 2025
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TBX2 protein acts as a switch to drive prostate cancer treatment resistance, study finds
According to the American Cancer Society, approximately 1 in 8 men in the U.S. will be diagnosed with prostate cancer during their lifetime. In addition, about 1 in 44 men will die from the disease, placing it second behind ...
Mar 27, 2025
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DNA from the mother and father are handled differently in the newly formed embryo, researchers discover
Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in their development. New insights into how maternal and paternal DNA is replicated during the initial ...
Mar 27, 2025
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Gene editing with adeno-associated virus vector offers hope for hereditary deafness
An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent cells and leading to syndromic hearing loss. In a new experimental study, scientists from Juntendo ...
Mar 27, 2025
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Research offers reassurance for patients with some cancer-linked genes
As more people receive genetic testing after a cancer diagnosis, newer variants have been identified that increase the risk of developing cancer. A recent study led by the University of Michigan Rogel Cancer Center finds ...
Mar 27, 2025
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Knowledge of genetics and genomic medicine is crucial for mental health providers, says study
In a manuscript published in the American Journal of Psychiatry titled "Psychiatric Genetics in Clinical Practice: Essential Knowledge for Mental Health Professionals," the authors provide updated guidelines on what mental ...
Mar 27, 2025
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'Sky is not falling' over 23andMe bankruptcy, says expert
On March 23, direct-to-consumer genetic testing company 23andMe announced it had filed for bankruptcy. The move came after the company, which generated genetic profiles based on saliva samples from customers, faced financial ...
Mar 27, 2025
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How inherited cancer risks can be used for effective personalized therapy
Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition to develop breast cancer, ovarian, prostate, pancreatic, and other epithelial tumors.
Mar 26, 2025
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